Negative-stained Transmission Electron Micrograph (TEM) demonstrating the brick-shaped monkeypox virus from a cell culture. The surface mulberry virion (right) are covered with short, whorled filaments, while capsular virions (left) penetrated by stain present as a sharply defined, dense core surrounded by several laminated zones of differing densities. Monkeypox virus (MPV) is a double-stranded DNA, zoonotic virus and a species of the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. Bu
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Negative-stained Transmission Electron Micrograph (TEM) demonstrating the brick-shaped monkeypox virus from a cell culture. The surface mulberry virion (right) are covered with short, whorled filaments, while capsular virions (left) penetrated by stain present as a sharply defined, dense core surrounded by several laminated zones of differing densities. Monkeypox virus (MPV) is a double-stranded DNA, zoonotic virus and a species of the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. But it is not a direct ancestor to, nor a direct descendent of, the variola virus which causes smallpox. The monkeypox virus causes a disease that is similar to smallpox, but with a milder rash and lower death rate. Variation in virulence of the virus has been observed in isolates from Central Africa where strains are more virulent than those from Western Africa. Magnification: unknown.